The GTX 645 is comparable to other mid-range GPUs from its time, such as the AMD Radeon HD 7770 and the NVIDIA GeForce GTX 650.
Without a specific context, here's a speculative write-up: vec645 hot
If your input voltage is high (say, 48V), add a simple switching pre-regulator to drop it to 12V before feeding the VEC645. The VEC645 then only dissipates heat from 12V to 5V, a 7V drop instead of 43V—a sixfold reduction in heat generation. The GTX 645 is comparable to other mid-range
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